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Diablo 4 Season 10: Best Route to Diablo 4 Items Farm Lair Boss Materials Fast

An essential part of Diablo 4's endgame is challenging the game's devastating Lair Bosses-elite endgame encounters that reward players with build-defining Mythic gear. Once players reach Torment 1 difficulty, they gain access to the Lair Boss ladder, where each victory can yield some of the most powerful Uniques and Mythics in the game. However, these bosses aren't simple loot pinatas-you'll need specific boss materials to unlock the rewards from their loot chests after defeating them.

For players aiming to farm Lair Bosses efficiently in Diablo 4 Season 10, the key lies in gathering boss materials first. Unfortunately, these materials aren't guaranteed drops, but there's a highly effective two-step farming strategy that maximizes your chances. By combining Helltides and the Kurast Undercity from the Vessel of Hatred DLC, players can reliably stockpile every material needed for the Initiate, Greater, and even Exalted Lair Bosses.

Here's the ideal farming progression path:

1. Farm Initiate Boss materials via Helltides and Undercity runs.
2. Defeat Initiate Bosses to earn Greater materials.
3. Challenge Greater Bosses (like Duriel and Andariel) for a chance at Belial's Betrayer's Husk, used for Exalted chests.

This structured approach ensures you're always progressing upward, never wasting time farming bosses without the materials to open their reward caches.

Final Tips for Efficient Boss Material Farming

Always farm during active Helltides-they offer the best density and drop rates.
Party up to increase Tribute and material yield per hour.
Keep Baneful Hearts and Tributes of Titans stocked up at all times.
Prioritize Initiate Bosses if you want Mythics faster, since their fights are quicker and their drops feed directly into Greater Boss progression.
Consider buying D4 materials from eld.gg if you're missing specific Mythic components or materials.

By following this Helltide + Undercity loop, Diablo 4 Season 10 players can build up a steady supply of boss materials and enjoy near-constant Lair Boss access. With the right setup, you'll not only unlock Mythic gear faster but also stand ready for cheap Diablo IV gold the ultimate challenge-Beial, Lord of Lies, the Exalted Lair Boss of the Vessel of Hatred DLC.